Sickle Cell Disease Genomics Network of Africa
Research Projects (Project 1)
To determine the variation in the levels of five major haemolysis
cytoprotective proteins in SCD by studying a cohort of 7,000 patients from six cities
Ghana, Nigeria and Tanzania. To document the prevalence of acute damage to major
organs during hospitalization of SCD patients in a cohort of 7,000 SCD patients. To
catalogue genome-wide variants associated with the levels of the five haemolysis
cytoprotective in SCD patients. To provide evidence in support or against the idea that
SCD patients with higher plasma concentrations of haemolysis cytoprotective proteins
have a lower risk than age- and gender-matched counterparts in developing acute
damage to major organs during VOC and hyper hemolysis.
SickleGenAfrica is funded by NIH Common Fund Award / NHLBI Grant Number U54HL141011
The SickleGenAfrica website content is solely the responsiblity of the authors and does not necessarily represent the official views of the National Institutes of Health.
Sickle Cell Disease Genomics Network of Africa (SickleGenAfrica).
SickleGenAfrica: A research network of the H3Africa consortium
September 24, 2018
September 10, 2018
Get in Touch
Administration & Examination Hall Building.
School of Biomedical and Allied Health Sciences.
University of Ghana,
Korle Bu, Accra, Ghana
Telephone: +233 30 397 0949
Justina Agula, MSc
Telephone: +233 24 814 9499
© 2017 SickleGenAfrica