Project 3


Sickle Cell Disease Genomics Network of Africa

Research Projects (Project 3)

To phenotype major echo-cardiovascular biomarkers (cardiac dilation,

cardiac index, blood pressure, diastolic dysfunction, tricuspid jet regurgitation velocity

(TRJV) and RV dysfunction) in 2,000 adults with SCD patients from West and East

Africa. To catalogue genetic variants associated with the aforementioned echo-

cardiovascular phenotypes in adult SCD patient. To determine whether polymorphism

associated with HCP levels are linked to specific echo-cardiovascular phenotypes.


Administration & Examination Hall Building.

School of Biomedical and Allied Health Sciences.

University of Ghana,

Korle Bu, Accra, Ghana

+233 303 970949


SickleGenAfrica is funded by NIH Common Fund Award / NHLBI Grant Number U54HL141011

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