Project 3


Sickle Cell Disease Genomics Network of Africa

Research Projects (Project 3)

To phenotype major echo-cardiovascular biomarkers (cardiac dilation,

cardiac index, blood pressure, diastolic dysfunction, tricuspid jet regurgitation velocity

(TRJV) and RV dysfunction) in 2,000 adults with SCD patients from West and East

Africa. To catalogue genetic variants associated with the aforementioned echo-

cardiovascular phenotypes in adult SCD patient. To determine whether polymorphism

associated with HCP levels are linked to specific echo-cardiovascular phenotypes.

SickleGenAfrica is funded by NIH Common Fund Award / NHLBI Grant Number U54HL141011

The SickleGenAfrica website content is solely the responsiblity of the authors and does not necessarily represent the official views of the National Institutes of Health.


Sickle Cell Disease Genomics Network of Africa (SickleGenAfrica).

SickleGenAfrica: A research network of the H3Africa consortium

Get in Touch

Administration & Examination Hall Building.

School of Biomedical and Allied Health Sciences.

University of Ghana,

Korle Bu, Accra, Ghana

Telephone: +233 30 397 0949

Project Manager

Justina Agula, MSc

Telephone: +233 24 814 9499

© 2017 SickleGenAfrica